L-ornithine plays a central role in the urea cycle which converts ammonia to urea in the liver. L-ornithine administration has been known to enhance detoxification of ammonia in the liver.

L-arginine is converted in the body into a chemical called nitric oxide. Nitric oxide causes blood vessels to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances in the body.

L-citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body.